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Heart Failure
~7.72 million patients have heart failure in the United States5
CKD with T2D
~40% of the 36.4 million Americans with T2D will develop CKD9,10
ACCORD, Action to Control Cardiovascular Risk in Diabetes; CKD, chronic kidney disease;
ICD-10, International Classification of Diseases, Tenth Revision; NHANES, National Health and Nutrition Examination Survey; T2D, type 2 diabetes.
*Retrospective study of 60,514 adults ≥18 years in the Nationwide Readmission Database who were hospitalized for acute or acute on chronic HFpEF according to an ICD-10 diagnosis code of I5031 or acute on chronic HFpEF.8
†Longitudinal study of 39,982 patients ≥65 years in the Get With The Guidelines®-Heart Failure registry, linked with U.S. Centers for Medicare & Medicaid Services claims data from Jan 1, 2005 through Dec 30, 2009.2
‡Multicenter randomized controlled study of 12,537 high-risk patients with prediabetes or early T2D.11
§Retrospective analysis of the ACCORD trial, a randomized study of 10,251 patients with T2D.12
¶Cross-sectional analysis of adults with T2D from 3 US NHANES datasets developed during 2007-2012.13
References: 1. Bozkurt B, et al. J Card Fail. 2025;31(1):66-116. 2. Shah KS, et al. J Am Coll Cardiol. 2017;70(20):2476-2486. 3. Wu B, et al. BMJ Open Diabetes Res Care. 2016;4(1):e000154. 4. Schrauben SJ, et al. PLoS Med. 2020;17(12):e1003470. 5. Racine M, et al. CardioVascular Resource Group. CVrg Market Strategies Heart Failure 4Q 2024. 6. Olchanski N, et al. Cardiovasc Endocrinol Metab. 2020;9(1):17-23. 7. Racine M, et al. CardioVascular Resource Group. CVrg Market Strategies Heart Failure 3Q 2024. 8. Jha AK, et al. World J Cardiol. 2022;14(9):473-482. 9. Centers for Disease Control and Prevention. National Diabetes Statistics Report. Accessed April 15, 2025. https://www.cdc.gov/diabetes/php/data-research/index.html#:~:text=Prevalence%20of%20both%20diagnosed%20and,the%20U.S.%20population—had%20diabetes 10. Bailey RA, et al. BMC Res Notes. 2014;7:415. 11. Papademetriou V, et al. Am J Med. 2017;130(12):1465.e27-1465.e39. 12. Papademetriou V, et al. Kidney Int. 2015;87(3):649-659. 13. Wu B, et al. BMJ Open Diabetes Res Care. 2016;4(1):e000154. 14. American Diabetes Association Professional Practice Committee. Diabetes Care. 2025;48(suppl 1):S239-S251. 15. Alfego D, et al. Diabetes Care. 2021;44(9):2025-2032.
